Huaier Granule

Huaier Granule is also named huaier keli. which is recommended for inoperable primary liver cancer or as Adjuvant therapy for chemotherapy.

Huaier Granule Functions

Tonify and improve body energy. promoting blood circulation and eliminating lump.

Huaier Granule was specially approved as a special drug for the treatment of cancer deficiency in 2022.

Huaier Granule Introduction

Huaier Granule, is a traditional Chinese herbal medicine made from the fungus Trametes versicolor, commonly known as Yunzhi or Turkey Tail mushroom.  It has been used for centuries in traditional Chinese medicine for its potential health benefits.

Huaier Granule is prepared by extracting and processing the fruiting bodies of Trametes versicolor into a concentrated powder or granular form.  It contains various bioactive compounds, including polysaccharides, triterpenoids, and other secondary metabolites, which are believed to contribute to its medicinal properties.

This herbal medicine has gained attention for its potential anticancer properties.  Some research studies have suggested that Huaier Granule may have antitumor effects by inhibiting the growth and spread of cancer cells, promoting apoptosis (programmed cell death), and modulating the immune system.  However, it's important to note that further scientific studies are needed to fully understand its mechanisms of action and effectiveness in different types of cancer.

Apart from its potential anticancer properties, Huaier Granule has also been studied for its potential benefits in other areas, including liver health, immune modulation, and anti-inflammatory effects.  However, it's important to consult with a healthcare professional or traditional Chinese medicine practitioner for appropriate usage and dosage recommendations.

As with any herbal medicine, it's crucial to be aware of potential side effects, drug interactions, and individual variations in response.  If you're considering using Huaier Granule or any herbal remedy, it's always recommended to seek guidance from a qualified healthcare professional with knowledge and experience in traditional Chinese medicine.

Huaier Granule Indications

for inoperable primary liver cancer or as Adjuvant therapy for chemotherapy. relieve liver pain, bloating, fatigue and other symptoms. On the basis of standard anti-lump chemicals treatment can be used for lung lump, gastrointestinal lump and breast lump induced lassitude,mental fatigue, abdominal pain or swelling, nausea , dry stools or loose stools, or shortness of breath, cough,more sputum, pale, chest pain, bloody sputum, chest and ribs discomfort, improve the patients life quality.

How to Take Huaier Granule

Oral use 30 mins before meal . 20g one time and 3 times one day. Usually 1 month (15 packs) as one course.

About Packages

Experience package including 6 packs with 108 capsules which may last 9 days.

1 course package including 10 packs with 360 capsules which may last 30 days.

2 courses package including 20 packs with 720 capsules which may last 60 days.

Huaier Granule Studies and Researches

Huaier Granule, derived from the Trametes versicolor fungus, has been the subject of several studies and research regarding its potential health benefits.  While it's important to note that research is ongoing and some studies may have limitations, here are a few key findings:

Anticancer Effects

Multiple studies have investigated the potential anticancer properties of Huaier Granule.  Research suggests that it may inhibit the growth and metastasis of various cancer types, including liver, lung, breast, colon, and gastric cancers.

Huaier Granule has been found to induce apoptosis (programmed cell death) in cancer cells and inhibit cancer cell proliferation.

It may also have immunomodulatory effects by enhancing the activity of immune cells, such as natural killer (NK) cells and T lymphocytes.

Liver Health

Studies have explored the hepatoprotective effects of Huaier Granule.  It may help protect the liver from damage caused by toxins, viruses (such as hepatitis B and C), and other factors.

Huaier Granule has been found to exhibit anti-inflammatory and antioxidative properties, which may contribute to its liver-protective effects.

Anti-inflammatory and Immunomodulatory Effects:

Huaier Granule has been shown to possess anti-inflammatory properties by inhibiting the release of pro-inflammatory molecules and reducing the activation of inflammatory pathways.

It may also modulate the immune system by promoting the production of immune-regulating cytokines and enhancing immune cell activity.

It's worth noting that while these studies suggest potential benefits of Huaier Granule, more rigorous clinical trials and larger-scale studies are needed to establish its efficacy, determine optimal dosage, and understand its mechanisms of action better.

Pharmacology and toxicology

1.Can activate macrophages, activated macrophages can kill tumor cells, treatment, presented tumor antigen to activate T cells produce specific anti-tumor effect, but also by ADCC (antibody-dependent cytotoxicity ) Kill tumor cells, macrophages release TNF-¦Á, IL-1, IFN-¦Á and other cytokines, regulating anti-tumor response, serum lysozyme activity also reflects the activity of macrophages.

2. Induced cytokines: Monocyte-derived macrophages produce TNF-¦Á, TL-1, CSF (colony stimulating factor), etc. can be activated to enhance the phagocytic killing effect and inhibit tumor growth. TNF-alpha also enhances the activity of NK cells (natural killer cells) and CTLs (cytotoxic T cells). T cells can produce IFN-¦Ã, IL-2 and so on. IL-2 can stimulate the growth and proliferation of T and B lymphocytes, so that activated T cells can secrete IFN-¦Ã and CSFS, and these cytokines can enhance cytotoxic activity of CTL, NK cells and macrophages and induce LAK Factor-activated killer cells), TIL (tumor-infiltrating lymphocytes). The synergistic effect of these cytokines can enhance T cell, macrophage, NK cell killing ability of tumor cells.

3. Promote cellular immunity: Huayi Er on cord blood EaRF (reactive rosette) and GvHR (graft versus host reaction) have an enhanced role, indicating that T cell activity increased, while interferon, especially the synergistic effect of IFN-¦Ã , NK cell activity increased, thereby enhancing the Huai'er particles on the tumor killing effect.

4. Improve the production of specific antibodies: the role of antibodies, phagocytic phagocytosis and increase the phagocytic role of play ADCC, the tumor cells were killed, phagocytosed or dissolved.

5.In addition, but also to promote the synthesis of DNA in mouse spleen cells, increase the content of hemoglobin in serum, etc., have a certain role in promoting hematopoietic cells. Unlike cytokine therapy, cytokines such as IFN-¦Á, IFN-¦Ã, and IL-2, which are induced by Sophora flavescens, are endogenous and have low-dose, multi-stimulating and combined effects among them Obvious effect.

The difference of Adjuvant therapy/cancer medicines